CART cell therapy
Overview
Chimeric antigen receptor (CAR) T-cell therapy is a cancer treatment that uses a patient's own T cells to fight cancer. CAR T cells are genetically modified in a lab to recognize and kill cancer cells.
How it works
- T cells are collected from the patient's blood
- The T cells are genetically modified in a lab to produce chimeric antigen receptors (CARs) on their surface
- Millions of CAR T cells are grown in the lab
- The CAR T cells are infused back into the patient
- The CAR T cells bind to antigens on cancer cells and kill them
What it treats
CAR T-cell therapy is effective against some types of cancer, including leukemia, lymphoma, and multiple myeloma. It can be very effective even when other treatments aren't working.
Limitations
CAR T-cell therapy doesn't work for every patient. Some patients have benefited for a short time before relapsing. There are also risks of CAR T-cell-associated toxicities.